A murine model of interlamellar corneal transplantation
نویسندگان
چکیده
منابع مشابه
A primate model of human corneal transplantation.
Human donor corneas were used for penetrating keratoplasty in one eye of each of 12 rhesus monkeys. In six animals, a 9.5-mm cornea was sutured into a 9.0-mm recipient bed by means of interrupted 10-0 nylon sutures. Six other animals received a 6.5-mm cornea in a 6.0-mm bed. Biomicroscopy, pachymetry, and specular microscopy revealed two distinct healing patterns. Of the six eyes receiving the ...
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PURPOSE To evaluate the role that delayed-type hypersensitivity (DTH) and cytotoxic T lymphocyte responses play in a murine model of orthotopic corneal allograft transplantation. METHODS Corneal transplantation was performed by grafting C57BL/6 donor corneas into BALB/c corneal beds. After transplantation, the mice were observed by slit lamp biomicroscopy on a weekly basis and graded for sign...
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Interlamellar plastic discs inserted into cat corneas provide a means by which segments of the cornea can be studied with regard to swelling and water movement in vivo. The corneas are physiologically normal as demonstrated by their transparency, swelling properties, and histologic structure. The observation that one disc causes no change in the hydration of the stroma anterior or posterior to ...
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deployable scissor type structures are composed of the so-called scissor-like elements (sles), which are connected to each other at an intermediate point through a pivotal connection and allow them to be folded into a compact bundle for storage or transport. several sles are connected to each other in order to form units with regular polygonal plan views. the sides and radii of the polygons are...
Optimizing rejection readouts in a corneal allograft transplantation model
PURPOSE To evaluate the feasibility of anterior segment spectral domain optic coherence tomography (ASOCT) as rejection readout in a keratoplasty mouse model and to compare ASOCT against the current standard (i.e., a clinical score system). Furthermore, to compare both approaches with respect to intra- and inter-individual observer variability and to calculate a critical point that distinguishe...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1998
ISSN: 0007-1161
DOI: 10.1136/bjo.82.3.294